SYSTEMIC EFFECTS OF INTRA-ARTICULAR INJECTION OF HYDROCORTISONE ACETATE

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Studies in osteo-arthritis using intra-articular temperature response to injection of hydrocortisone acetate and prednisone.

The use of intra-articular hydrocortisone acetate in the treatment of osteo-arthritis has been shown to produce a temporary improvement of symptoms in many cases (Hollander, Stoner, Brown, and De Moor, 1951), although enthusiasm for this method has been tempered by warnings of the possibility of increasing the damage in joints subjected to excessive use in the periods of freedom from symptoms (...

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Intra-articular hydrocortisone (compound F) acetate; a preliminary report.

The suppression of inflammation in the joint structures of patients with rheumatoid arthritis by cortisone acetate administered systemically is well known. Hydrocortisone acetate, formerly known as Compound F acetate (17-hydroxycorticosterone-21-acetate), administered orally or intramuscularly, has recently been shown to have a similar suppressive effect upon this inflammation (Ward and others,...

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Intra-articular therapy in osteo-arthritis; comparison of hydrocortisone acetate and hydrocortisone tertiary-butylacetate.

The intra-articular injection of hydrocortisone acetate is commonly used in the treatment of osteoarthritis, although its action in this disease has received less careful study than in rheumatoid arthritis. In 1955 a less soluble ester, hydrocortisone tertiary-butylacetate (TBA) was developed for intraarticular therapy with the claim that its effects were more pronounced and of longer duration ...

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Intra-articular hydrocortisone in osteo-arthrosis.

There is no doubt about the value of intraarticular hydrocortisone in the treatment of rheumatoid arthritis. Controversy has arisen however about its value in the treatment of osteo-arthrosis. Hollander, who introduced this useful form of therapy, has remained an advocate of its use in both conditions (Hollander, 1966). Because of the lack of distinction between the response in patients with rh...

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ژورنال

عنوان ژورنال: Endocrinologia Japonica

سال: 1957

ISSN: 0013-7219,2185-6370

DOI: 10.1507/endocrj1954.4.57